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Inducers of Hypoxic Response: Marine Sesquiterpene Quinones Activate HIF-1
The hypoxia-inducible factor-1 (HIF-1) transcription factor regulates cellular oxygen homeostasis. Agents that activate HIF-1 and downstream HIF targets represent potential drug leads for the prevention and/or treatment of ischemic disorders. In a search for small-molecule HIF-1 activators, 1936 mar...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718637/ https://ncbi.nlm.nih.gov/pubmed/23731014 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/np400320r |
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