Activation in vitro of rheumatoid synovial collagenase from cell cultures.

Rheumatoid synovial cells dissociated from matrix and adherent to culture dishes released a latent form of collagenase into culture medium. Previous studies have shown that the latent enzyme does not complex with alpha2-macroglobulin and binds to fibrillar substrate. We now show that serum-free cult...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Vater, C A, Mainardi, C L, Harris, E D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1978
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371857/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/213448/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109228
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