Cobalamin Binding and Cobalamin-Dependent Enzyme Activity in Normal and Mutant Human Fibroblasts

We have studied the intracellular binding of radioactive cobalamin by normal cultured human fibroblasts grown in medium containing [(57)Co]-cobalamin. We have also assessed the significance of defects in this binding activity exhibited by two classes of human mutants (cbl C and cbl D) each character...

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Pubblicato in:	J Clin Invest
Autori principali:	Mellman, Ira, Willard, Huntington F., Rosenberg, Leon E.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1978
Soggetti:	Articles
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371853/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/30783/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109224
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