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Cobalamin Binding and Cobalamin-Dependent Enzyme Activity in Normal and Mutant Human Fibroblasts

We have studied the intracellular binding of radioactive cobalamin by normal cultured human fibroblasts grown in medium containing [(57)Co]-cobalamin. We have also assessed the significance of defects in this binding activity exhibited by two classes of human mutants (cbl C and cbl D) each character...

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Detalhes bibliográficos
Main Authors: Mellman, Ira, Willard, Huntington F., Rosenberg, Leon E.
Formato: Artigo
Idioma:Inglês
Publicado em: 1978
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC371853/
https://ncbi.nlm.nih.gov/pubmed/30783
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