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Purification and Fibrillation of Full-Length Recombinant PrP

Misfolding and aggregation of prion protein (PrP) is related to several neurodegenerative diseases in humans such as Creutzfeldt–Jacob disease, fatal familial insomnia, and Gerstmann–Straussler–Sheinker disease. Certain applications in prion area require recombinant PrP of high purity and quality. H...

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Bibliographic Details
Main Authors: Makarava, Natallia, Baskakov, Ilia V.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718478/
https://ncbi.nlm.nih.gov/pubmed/22528082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-551-0_4
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