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Purification and Fibrillation of Full-Length Recombinant PrP

Misfolding and aggregation of prion protein (PrP) is related to several neurodegenerative diseases in humans such as Creutzfeldt–Jacob disease, fatal familial insomnia, and Gerstmann–Straussler–Sheinker disease. Certain applications in prion area require recombinant PrP of high purity and quality. H...

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Bibliografiske detaljer
Main Authors: Makarava, Natallia, Baskakov, Ilia V.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718478/
https://ncbi.nlm.nih.gov/pubmed/22528082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-551-0_4
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