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Inhibition of erythrocyte sickling in vitro by pyridoxal.

To test the antisickling activity of pyridoxal, we compared the oxygen affinity and the percent sickling at low PO2 of untreated erythrocytes with values for cells from the same blood sample incubated with pyridoxal, glyceraldehyde, or pyridoxine. Pyridoxal increased oxygen affinity much more than g...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Kark, J A, Kale, M P, Tarassoff, P G, Woods, M, Lessin, L S
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1978
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371842/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/701485/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109202
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