Kalirin-7 Mediates Cocaine-Induced AMPA Receptor and Spine Plasticity, Enabling Incentive Sensitization

It is well established that behavioral sensitization to cocaine is accompanied by increased spine density and AMPA receptor (AMPAR) transmission in the nucleus accumbens (NAc), but two major questions remain unanswered. Are these adaptations mechanistically coupled? And, given that they can be disso...

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Detalhes bibliográficos
Main Authors: Wang, Xiaoting, Cahill, Michael E., Werner, Craig T., Christoffel, Daniel J., Golden, Sam A., Xie, Zhong, Loweth, Jessica A., Marinelli, Michela, Russo, Scott J., Penzes, Peter, Wolf, Marina E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718375/
https://ncbi.nlm.nih.gov/pubmed/23825406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1097-13.2013
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