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Individual Differences in Novelty Seeking Predict Subsequent Vulnerability to Social Defeat through a Differential Epigenetic Regulation of Brain-Derived Neurotrophic Factor Expression

Some personality traits, including novelty seeking, are good predictors of vulnerability to stress-related mood disorders in both humans and rodents. While high-novelty-seeking rats [high responders (HRs)] are vulnerable to the induction of depressive-like symptoms by social defeat stress, low-novel...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Duclot, Florian, Kabbaj, Mohamed
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718363/
https://ncbi.nlm.nih.gov/pubmed/23825410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0199-13.2013
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