Immune and Genetic Correlates of Vaccine Protection Against Mucosal Infection by SIV in Monkeys

The RV144 vaccine trial in Thailand demonstrated that an HIV vaccine could prevent infection in humans and highlights the importance of understanding protective immunity against HIV. We used a nonhuman primate model to define immune and genetic mechanisms of protection against mucosal infection by t...

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Hauptverfasser: Letvin, Norman L., Rao, Srinivas S., Montefiori, David C., Seaman, Michael S., Sun, Yue, Lim, So-Yon, Yeh, Wendy W., Asmal, Mohammed, Gelman, Rebecca S., Shen, Ling, Whitney, James B., Seoighe, Cathal, Lacerda, Miguel, Keating, Sheila, Norris, Philip J., Hudgens, Michael G., Gilbert, Peter B., Buzby, Adam P., Mach, Linh V., Zhang, Jinrong, Balachandran, Harikrishnan, Shaw, George M., Schmidt, Stephen D., Todd, John-Paul, Dodson, Alan, Mascola, John R., Nabel, Gary J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718279/
https://ncbi.nlm.nih.gov/pubmed/21543722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3002351
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