Ultrasound-enhanced delivery of Morpholino with Bubble liposomes ameliorates the myotonia of myotonic dystrophy model mice

Phosphorodiamidate morpholino oligonucleotide (PMO)-mediated control of the alternative splicing of the chloride channel 1 (CLCN1) gene is a promising treatment for myotonic dystrophy type 1 (DM1) because the abnormal splicing of this gene causes myotonia in patients with DM1. In this study, we opti...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Koebis, Michinori, Kiyatake, Tamami, Yamaura, Hiroshi, Nagano, Kanako, Higashihara, Mana, Sonoo, Masahiro, Hayashi, Yukiko, Negishi, Yoichi, Endo-Takahashi, Yoko, Yanagihara, Dai, Matsuda, Ryoichi, Takahashi, Masanori P., Nishino, Ichizo, Ishiura, Shoichi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718203/
https://ncbi.nlm.nih.gov/pubmed/23873129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02242
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados