An MLL-dependent network sustains hematopoiesis

The histone methyltransferase Mixed Lineage Leukemia (MLL) is essential to maintain hematopoietic stem cells and is a leukemia protooncogene. Although clustered homeobox genes are well-characterized targets of MLL and MLL fusion oncoproteins, the range of Mll-regulated genes in normal hematopoietic...

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Detalles Bibliográficos
Main Authors: Artinger, Erika L., Mishra, Bibhu P., Zaffuto, Kristin M., Li, Bin E., Chung, Elaine K. Y., Moore, Adrian W., Chen, Yufei, Cheng, Chao, Ernst, Patricia
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2013
Assuntos:
Biological Sciences
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718146/
https://ncbi.nlm.nih.gov/pubmed/23744037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1301278110
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