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Rickettsia Sca2 has evolved formin-like activity through a different molecular mechanism

Sca2 (surface cell antigen 2) is the only bacterial protein known to promote both actin filament nucleation and profilin-dependent elongation, mimicking eukaryotic formins to assemble actin comet tails for Rickettsia motility. We show that Sca2’s functional mimicry of formins is achieved through a u...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Madasu, Yadaiah, Suarez, Cristian, Kast, David J., Kovar, David R., Dominguez, Roberto
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718132/
https://ncbi.nlm.nih.gov/pubmed/23818602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307235110
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