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Rickettsia Sca2 has evolved formin-like activity through a different molecular mechanism
Sca2 (surface cell antigen 2) is the only bacterial protein known to promote both actin filament nucleation and profilin-dependent elongation, mimicking eukaryotic formins to assemble actin comet tails for Rickettsia motility. We show that Sca2’s functional mimicry of formins is achieved through a u...
Gorde:
Egile Nagusiak: | , , , , |
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Formatua: | Artigo |
Hizkuntza: | Inglês |
Argitaratua: |
National Academy of Sciences
2013
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Gaiak: | |
Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718132/ https://ncbi.nlm.nih.gov/pubmed/23818602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307235110 |
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