Context-dependent signaling defines roles of BMP9 and BMP10 in embryonic and postnatal development

Many important signaling pathways rely on multiple ligands. It is unclear if this is a mechanism of safeguard via redundancy or if it serves other functional purposes. In this study, we report unique insight into this question by studying the activin receptor-like kinase 1 (ALK1) pathway. Despite it...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chen, Hao, Brady Ridgway, John, Sai, Tao, Lai, Joyce, Warming, Søren, Chen, Hanying, Roose-Girma, Merone, Zhang, Gu, Shou, Weinian, Yan, Minhong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2013
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718114/
https://ncbi.nlm.nih.gov/pubmed/23812757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306074110
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