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Effects of Commonly Used Excipients on the Expression of CYP3A4 in Colon and Liver Cells
PURPOSE: The objective of this investigation was to assess whether common pharmaceutical excipients regulate the expression of drug-metabolizing enzymes in human colon and liver cells. METHODS: Nineteen commonly used excipients were evaluated using a panel of experiments including cell-based human P...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3718039/ https://ncbi.nlm.nih.gov/pubmed/20503067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-010-0170-2 |
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