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Biosynthesis of Chenodeoxycholic Acid in Man

Stereospecific side-chain hydroxylations of 5β-cholestane-3α, 7α-diol were studied in mitochondrial and microsomal fractions of human liver. Incubation of 5β-cholestane-3α, 7α-diol resulted in hydroxylations at C-12, C-24, C-25, and C-26. Hydroxylations at C-24 and C-26 were accompanied by the intro...

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Podrobná bibliografie
Vydáno v:J Clin Invest
Hlavní autoři: Shefer, S., Cheng, F. W., Batta, A. K., Dayal, B., Tint, G. S., Salen, G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1978
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371797/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/690184/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109158
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