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Heat Shock Protein 90 is overexpressed in high-risk myelodysplastic syndromes and associated with higher expression and activation of Focal Adhesion Kinase

Myelodysplastic syndromes are characterized by a high risk of evolution into acute myeloid leukaemia which can involve activation of signalling pathways. As the chaperone heat shock protein 90 (HSP90) has a key role in signal transduction, we investigated its role in the pathogenesis and evolution o...

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Detalhes bibliográficos
Main Authors: Flandrin-Gresta, Pascale, Solly, Françoise, Aanei, Carmen Mariana, Cornillon, Jérôme, Tavernier, Emmanuelle, Nadal, Nathalie, Morteux, Franck, Guyotat, Denis, Wattel, Eric, Campos, Lydia
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717957/
https://ncbi.nlm.nih.gov/pubmed/23047954
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