Cerebral Blood Flow and Glucose Metabolism Measured With Positron Emission Tomography Are Decreased in Human Type 1 Diabetes

Subclinical systemic microvascular dysfunction exists in asymptomatic patients with type 1 diabetes. We hypothesized that microangiopathy, resulting from long-standing systemic hyperglycemia and hyperinsulinemia, may be generalized to the brain, resulting in changes in cerebral blood flow (CBF) and...

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Main Authors: van Golen, Larissa W., Huisman, Marc C., Ijzerman, Richard G., Hoetjes, Nikie J., Schwarte, Lothar A., Lammertsma, Adriaan A., Diamant, Michaela
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2013
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717848/
https://ncbi.nlm.nih.gov/pubmed/23530004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-1159
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