Differential Regulation and Predictive Potential of MacroH2A1 Isoforms in Colon Cancer

Histone variant macroH2A1 has two splice isoforms, macroH2A1.1 and macroH2A1.2, with tissue- and cell-specific expression patterns. Although macroH2A1.1 is mainly found in differentiated, nonproliferative tissues, macroH2A1.2 is more generally expressed, including in tissues with ongoing cell prolif...

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Bibliographic Details
Main Authors: Sporn, Judith C., Jung, Barbara
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2012
Subjects:
Regular Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717782/
https://ncbi.nlm.nih.gov/pubmed/22542848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.02.027
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