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Different Adaptations in AMPA Receptor Transmission in the Nucleus Accumbens after Short vs Long Access Cocaine Self-Administration Regimens

Ca(2+)-permeable AMPA receptors (CP-AMPARs) accumulate in the nucleus accumbens (NAc) after ∼1 month of withdrawal from a long-access cocaine self-administration regimen (6 h/d, 10d). This is functionally significant because CP-AMPARs mediate the ‘incubated' cue-induced cocaine craving produced...

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Detalhes bibliográficos
Main Authors: Purgianto, Anthony, Scheyer, Andrew F, Loweth, Jessica A, Ford, Kerstin A, Tseng, Kuei Y, Wolf, Marina E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3717554/
https://ncbi.nlm.nih.gov/pubmed/23546386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2013.78
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