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Initial Fiber Alignment Pattern Alters Extracellular Matrix Synthesis in Fibroblast Populated Fibrin Gel Cruciforms and Correlates with Predicted Tension
Human dermal fibroblasts entrapped in fibrin gels cast in cross-shaped (cruciform) geometries with 1:1 and 1:0.5 ratios of arm widths were studied to assess whether tension and alignment of the cells and fibrils affected ECM deposition. The cruciforms of contrasting geometry (symmetric vs. asymmetri...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3717318/ https://ncbi.nlm.nih.gov/pubmed/21046467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-010-0192-2 |
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