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Refining comparative proteomics by spectral counting to account for shared peptides and multiple search engines
Spectral counting has become a widely used approach for measuring and comparing protein abundance in label-free shotgun proteomics. However, when analyzing complex samples, the ambiguity of matching between peptides and proteins greatly affects the assessment of peptide and protein inventories, diff...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3717168/ https://ncbi.nlm.nih.gov/pubmed/22552787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00216-012-6011-x |
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