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Secondary Structure in Denatured DNA is Responsible for Its Reaction with Antinative DNA Antibodies of Systemic Lupus Erythematosus Sera

Experiments were designed to determine the basis for the strong competitive reaction of denatured DNA with systemic lupus erythematosus (SLE) antinative DNA antibodies. Secondary structure in denatured DNA was reflected in hyperchromicity upon heating and in multiphase kinetics of its digestion by S...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Stollar, B. David, Papalian, Michael
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1980
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371700/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6156950/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109846
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