Evidence for biphasic uncoating during HIV-1 infection from a novel imaging assay

BACKGROUND: Uncoating of the HIV-1 core plays a critical role during early post-fusion stages of infection but is poorly understood. Microscopy-based assays are unable to easily distinguish between intact and partially uncoated viral cores. RESULTS: In this study, we used 5-ethynyl uridine (EU) to l...

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Autori principali: Xu, Hongzhan, Franks, Tamera, Gibson, Gregory, Huber, Kelly, Rahm, Nadia, De Castillia, Caterina Strambio, Luban, Jeremy, Aiken, Christopher, Watkins, Simon, Sluis-Cremer, Nicolas, Ambrose, Zandrea
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716918/
https://ncbi.nlm.nih.gov/pubmed/23835323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-70
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