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Direct in vitro effect of a sulfonylurea to increase human fibroblast insulin receptors.

We have studied the effects of the oral sulfonylurea agent glyburide to modulate insulin receptors on nontransformed human fibroblasts in tissue culture. When glyburide was added to monolayers of human fibroblasts, a dose-dependent increase in the number of cell surface receptors was observed with a...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Prince, M J, Olefsky, J M
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1980
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371691/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6772676/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109894
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