Evolution of the myosin heavy chain gene MYH14 and its intronic microRNA miR-499: muscle-specific miR-499 expression persists in the absence of the ancestral host gene

BACKGROUND: A novel sarcomeric myosin heavy chain gene, MYH14, was identified following the completion of the human genome project. MYH14 contains an intronic microRNA, miR-499, which is expressed in a slow/cardiac muscle specific manner along with its host gene; it plays a key role in muscle fiber-...

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Autors principals: Bhuiyan, Sharmin Siddique, Kinoshita, Shigeharu, Wongwarangkana, Chaninya, Asaduzzaman, Md, Asakawa, Shuichi, Watabe, Shugo
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716903/
https://ncbi.nlm.nih.gov/pubmed/24059862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-13-142
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