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LocARNAscan: Incorporating thermodynamic stability in sequence and structure-based RNA homology search

BACKGROUND: The search for distant homologs has become an import issue in genome annotation. A particular difficulty is posed by divergent homologs that have lost recognizable sequence similarity. This same problem also arises in the recognition of novel members of large classes of RNAs such as snoR...

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Autori principali: Will, Sebastian, Siebauer, Michael F, Heyne, Steffen, Engelhardt, Jan, Stadler, Peter F, Reiche, Backofen, Rolf
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716875/
https://ncbi.nlm.nih.gov/pubmed/23601347
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7188-8-14
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