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Trimethoxy-benzaldehyde levofloxacin hydrazone inducing the growth arrest and apoptosis of human hepatocarcinoma cells

BACKGROUND: In order to search for new structural modification strategies on fluoroquinolones, we have designed and synthesized a series of fluoroquinolone derivatives by linking various hydrazine compounds to the C-3 carboxyl group of levofloxacin and assessed their anticancer activities. Several n...

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書誌詳細
主要な著者: Sun, Jin-ping, Shi, Zhen-yu, Liu, Shi-meng, Kang, Yu-hua, Hu, Guo-qiang, Huangfu, Chao-shen, Deng, Jin-bo, Liu, Bin
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716872/
https://ncbi.nlm.nih.gov/pubmed/23819802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-67
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