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Phenolic and Tyrosyl Ring Deiodination of Iodothyronines in Rat Brain Homogenates

Conversion of thyroxine (T(4)) to 3,5,3′-triiodothyronine (T(3)) in rat brain has recently been shown in in vivo studies. This process contributes a substantial fraction of endogenous nuclear T(3) in the rat cerebral cortex and cerebellum. Production of T(4) metabolites besides T(3) in the brain has...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Kaplan, Michael M., Yaskoski, Kimberlee A.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1980
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371684/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7400328/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109887
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