HLA Class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients

Regulatory T cells (Tregs) play an important role in controlling antitumor T-cell responses and hence represent a considerable obstacle for cancer immunotherapy. The abundance of specific Treg populations in cancer patients has been poorly analyzed so far. Here, we demonstrate that in breast cancer...

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Bibliographic Details
Main Authors:	Schmidt, Hans-Henning, Ge, Yingzi, Hartmann, Felix J, Conrad, Heinke, Klug, Felix, Nittel, Sina, Bernhard, Helga, Domschke, Christoph, Schuetz, Florian, Sohn, Christof, Beckhove, Philipp
Format:	Artigo
Language:	Inglês
Published:	Landes Bioscience 2013
Subjects:	Original Research
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3716760/ https://ncbi.nlm.nih.gov/pubmed/23894725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24962
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HLA Class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients

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