HLA Class II tetramers reveal tissue-specific regulatory T cells that suppress T-cell responses in breast carcinoma patients

Regulatory T cells (Tregs) play an important role in controlling antitumor T-cell responses and hence represent a considerable obstacle for cancer immunotherapy. The abundance of specific Treg populations in cancer patients has been poorly analyzed so far. Here, we demonstrate that in breast cancer...

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Autores principales: Schmidt, Hans-Henning, Ge, Yingzi, Hartmann, Felix J, Conrad, Heinke, Klug, Felix, Nittel, Sina, Bernhard, Helga, Domschke, Christoph, Schuetz, Florian, Sohn, Christof, Beckhove, Philipp
Formato: Artigo
Lenguaje:Inglês
Publicado: Landes Bioscience 2013
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716760/
https://ncbi.nlm.nih.gov/pubmed/23894725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24962
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