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Engineering Grp170-based immune modulators for cancer immunotherapy

We have recently demonstrated that glucose-regulated protein 170 (Grp170), a stress-responsive molecular chaperone of the endoplasmic reticulum, can be exploited to stimulate anticancer immunity due to its superior antigen chaperoning and delivering capacity. The immune remodeling of the tumor micro...

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Detalhes bibliográficos
Main Authors: Yu, Xiaofei, Wang, Xiang-Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716734/
https://ncbi.nlm.nih.gov/pubmed/23894699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24385
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