The antitumor activity of a doxorubicin loaded, iRGD-modified sterically-stabilized liposome on B16-F10 melanoma cells: in vitro and in vivo evaluation

Considering the fact that iRGD (tumor-homing peptide) demonstrates tumor-targeting and tumor-penetrating activity, and that B16-F10 (murine melanoma) cells overexpress both αv integrin receptor and neuropilin-1 (NRP-1), the purpose of this study was to prepare a novel doxorubicin (DOX)-loaded, iRGD-...

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Detalhes bibliográficos
Main Authors: Yu, Ke-Fu, Zhang, Wei-Qiang, Luo, Li-Min, Song, Ping, Li, Dan, Du, Ruo, Ren, Wei, Huang, Dan, Lu, Wan-Liang, Zhang, Xuan, Zhang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716561/
https://ncbi.nlm.nih.gov/pubmed/23885174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S46962
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