Direct action of rat urinary kallikrein on rat kidney to release renin.

To study the effect of kallikrein on renal renin release, we superfused rat renal cortical slices with 3.5 to 140 milliesterase units (mEU)/ml of purified rat urinary kallikrein. Kallikrein was a potent stimulus of renin release. Renin rose in a dose-dependent fashion from 70 mEU/ml to 140 mEU/ml. T...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Suzuki, S, Franco-Saenz, R, Tan, S Y, Mulrow, P J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1980
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371650/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6999034/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109913
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