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Thalamic glutamate/glutamine in restless legs syndrome: Increased and related to disturbed sleep

OBJECTIVE: To evaluate possible abnormal increase in thalamic glutamate/glutamine levels for restless legs syndrome (RLS) indicating increased glutamatergic activity producing arousal that at night disrupts and shortens sleep. METHODS: (1)H MRS of the right thalamus was performed using a 1.5 T GE MR...

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Detalhes bibliográficos
Main Authors: Allen, Richard P., Barker, Peter B., Horská, Alena, Earley, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716406/
https://ncbi.nlm.nih.gov/pubmed/23624560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e318294b3f6
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