In Vivo Efficacy of Daptomycin against Methicillin-Resistant Staphylococcus aureus in a Mouse Model of Hematogenous Pulmonary Infection

Daptomycin is inactivated by pulmonary surfactant, but its effectiveness in hematogenous pulmonary infection has been poorly studied. The potential therapeutic application was evaluated in a methicillin-resistant Staphylococcus aureus (MRSA) hematogenous pulmonary infection mouse model. Compared wit...

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Hauptverfasser: Harada, Yosuke, Yanagihara, Katsunori, Yamada, Koichi, Migiyama, Yohei, Nagaoka, Kentaro, Morinaga, Yoshitomo, Nakamura, Shigeki, Imamura, Yoshifumi, Hasegawa, Hiroo, Miyazaki, Taiga, Izumikawa, Koichi, Kakeya, Hiroshi, Kohno, Shigeru
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2013
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716188/
https://ncbi.nlm.nih.gov/pubmed/23507279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02331-12
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