Severe Soft Tissue Infection Caused by a Non-Beta-Hemolytic Streptococcus pyogenes Strain Harboring a Premature Stop Mutation in the sagC Gene

We recovered a non-beta-hemolytic Streptococcus pyogenes strain from a severe soft tissue infection. In this isolate, we detected a premature stop codon within the sagC gene of the streptolysin S (SLS) biosynthetic operon. Reintroduction of full-length sagC gene on a plasmid vector restored the beta...

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Detalhes bibliográficos
Main Authors: Jantsch, Jonathan, Gerlach, Roman G., Ensser, Armin, Dahesh, Samira, Popp, Isabel, Heeg, Christiane, Bleiziffer, Oliver, Merz, Thomas, Schulz, Theresia, Horch, Raymund E., Bogdan, Christian, Nizet, Victor, van der Linden, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Case Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716101/
https://ncbi.nlm.nih.gov/pubmed/23515542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.00175-13
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