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Pathways of Infusate Loss During Convection Enhanced Delivery into the Putamen Nucleus

BACKGROUND: New strategies aiming to treat Parkinson’s disease such as delivery of trophic factors via protein infusion or gene transfer depend upon localized intracerebral infusion, mainly into the putamen nucleus. Convection enhanced delivery (CED) has been proposed as method to improve intracereb...

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Detalhes bibliográficos
Main Authors: Brady, Martin L., Raghavan, Raghu, Alexander, Andrew, Kubota, Ken, Sillay, Karl, Emborg, Marina E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716010/
https://ncbi.nlm.nih.gov/pubmed/23344643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000342492
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