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USING DNASE DIGESTION DATA TO ACCURATELY IDENTIFY TRANSCRIPTION FACTOR BINDING SITES

Identifying binding sites of transcription factors (TFs) is a key task in deciphering transcriptional regulation. ChIP-based methods are used to survey the genomic locations of a single TF in each experiment. But methods combining DNase digestion data with TF binding specificity information could po...

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Detalhes bibliográficos
Main Authors: LUO, KAIXUAN, HARTEMINK, ALEXANDER J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716004/
https://ncbi.nlm.nih.gov/pubmed/23424114
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