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Co-encapsulation of anti-BMP2 monoclonal antibody and mesenchymal stem cells in alginate microspheres for bone tissue engineering

Recently, it has been shown that tethered anti-BMP2 monoclonal antibodies (mAbs) can trap BMP ligands and thus provide BMP inductive signals for osteo-differentiation of progenitor cells. The objectives of this study were to: (1) develop a co-delivery system based on murine anti-BMP2 mAb-loaded algi...

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Detalhes bibliográficos
Main Authors: Moshaverinia, Alireza, Ansari, Sahar, Chen, Chider, Xu, Xingtian, Akiyama, Kentaro, Snead, Malcolm L., Zadeh, Homayoun H., Shi, Songtao
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715959/
https://ncbi.nlm.nih.gov/pubmed/23773817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2013.05.048
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