High Levels of S100A8/A9 Proteins Aggravate Ventilator-Induced Lung Injury via TLR4 Signaling

BACKGROUND: Bacterial products add to mechanical ventilation in enhancing lung injury. The role of endogenous triggers of innate immunity herein is less well understood. S100A8/A9 proteins are released by phagocytes during inflammation. The present study investigates the role of S100A8/A9 proteins i...

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Autori principali: Kuipers, Maria T., Vogl, Thomas, Aslami, Hamid, Jongsma, Geartsje, van den Berg, Elske, Vlaar, Alexander P. J., Roelofs, Joris J. T. H., Juffermans, Nicole P., Schultz, Marcus J., van der Poll, Tom, Roth, Johannes, Wieland, Catharina W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715539/
https://ncbi.nlm.nih.gov/pubmed/23874727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0068694
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