Phorbol diester-induced macrophage differentiation of leukemic blasts from patients with human myelogenous leukemia.
Phorbol esters, including 12-O-tetradecanoylphorbol 13-acetate (TPA), induce terminal macrophagelike differentiation of cells from human acute myelogenous leukemia lines. We report that myelogenous leukemia cells obtained from patients undergo macrophagelike differentiation after exposure to TPA. Th...
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| Published in: | J Clin Invest |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Clinical Investigation
1980
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371548/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6253522/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109939 |
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