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The Footprint of Genome Architecture in the Largest Genome Expansion in RNA Viruses

The small size of RNA virus genomes (2-to-32 kb) has been attributed to high mutation rates during replication, which is thought to lack proof-reading. This paradigm is being revisited owing to the discovery of a 3′-to-5′ exoribonuclease (ExoN) in nidoviruses, a monophyletic group of positive-strand...

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Detalhes bibliográficos
Main Authors: Lauber, Chris, Goeman, Jelle J., Parquet, Maria del Carmen, Thi Nga, Phan, Snijder, Eric J., Morita, Kouichi, Gorbalenya, Alexander E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715407/
https://ncbi.nlm.nih.gov/pubmed/23874204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003500
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