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Creation and implementation of a historical controls database from randomized clinical trials
BACKGROUND: Ethical concerns about randomly assigning patients to suboptimal or placebo arms and the paucity of willing participants for randomization into control and experimental groups have renewed focus on the use of historical controls in clinical trials. Although databases of historical contro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Publishing Group
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3715354/ https://ncbi.nlm.nih.gov/pubmed/23449762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/amiajnl-2012-001257 |
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