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Receptor-directed inhibition of chemotactic factor-induced neutrophil hyperactivity by pyrazolon derivatives. Definition of a chemotactic peptide antagonist.

The two pyrazolon derivatives, phenylbutazone and sulfinpyrazone, selectively inhibit chemotactic peptide-induced effects on neutrophils. As they antagonize the induction of acute neutropenia in vivo and of cellular hyperadhesiveness, lysosomal enzyme release, hexose monophosphate shunt activity, an...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
-д хэвлэсэн:J Clin Invest
Үндсэн зохиолчид: Dahinden, C, Fehr, J
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: American Society for Clinical Investigation 1980
Нөхцлүүд:
Онлайн хандалт:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371522/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7430350/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109955
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