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The role of reactive oxygen species and proinflammatory cytokines in type 1 diabetes pathogenesis
Type 1 diabetes (T1D) is a T cell–mediated autoimmune disease characterized by the destruction of insulin-secreting pancreatic β cells. In humans with T1D and in nonobese diabetic (NOD) mice (a murine model for human T1D), autoreactive T cells cause β-cell destruction, as transfer or deletion of the...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3715103/ https://ncbi.nlm.nih.gov/pubmed/23323860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1749-6632.2012.06826.x |
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