The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice

Oxygen depletion (O(2)) and a decrease in pH are initial pathophysiological events in stroke development, but secondary mechanisms of ischemic cell death are incompletely understood. By patch-clamp recordings of brain slice preparations we show that TASK1 and TASK3 channels are inhibited by pH-reduc...

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Autori principali: Meuth, Sven G., Kleinschnitz, Christoph, Broicher, Tilman, Austinat, Madeleine, Bräuninger, Stefan, Bittner, Stefan, Fischer, Stephan, Bayliss, Douglas A., Budde, Thomas, Stoll, Guido, Wiendl, Heinz
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714864/
https://ncbi.nlm.nih.gov/pubmed/18930826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.09.006
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