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Planar Cell Polarity Protein Celsr1 Regulates Endothelial Adherens Junctions and Directed Cell Rearrangements during Valve Morphogenesis

Planar cell polarity (PCP) signaling controls tissue morphogenesis by coordinating collective cell behaviors. We show a critical role for the core PCP proteins Celsr1 and Vangl2 in the complex morphogenetic process of intraluminal valve formation in lymphatic vessels. We found that valve-forming end...

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Detalhes bibliográficos
Main Authors: Tatin, Florence, Taddei, Andrea, Weston, Anne, Fuchs, Elaine, Devenport, Danelle, Tissir, Fadel, Makinen, Taija
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714594/
https://ncbi.nlm.nih.gov/pubmed/23792146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.05.015
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