Structural Basis for LMO2-Driven Recruitment of the SCL:E47(bHLH) Heterodimer to Hematopoietic-Specific Transcriptional Targets

Cell fate is governed by combinatorial actions of transcriptional regulators assembling into multiprotein complexes. However, the molecular details of how these complexes form are poorly understood. One such complex, which contains the basic-helix-loop-helix heterodimer SCL:E47 and bridging proteins...

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Main Authors: El Omari, Kamel, Hoosdally, Sarah J., Tuladhar, Kapil, Karia, Dimple, Hall-Ponselé, Elisa, Platonova, Olga, Vyas, Paresh, Patient, Roger, Porcher, Catherine, Mancini, Erika J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714592/
https://ncbi.nlm.nih.gov/pubmed/23831025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.06.008
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