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Myeloid depletion of SOCS3 enhances LPS-induced acute lung injury through CCAAT/enhancer binding protein δ pathway

Although uncontrolled inflammatory response plays a central role in the pathogenesis of acute lung injury (ALI), the precise molecular mechanisms underlying the development of this disorder remain poorly understood. SOCS3 is an important negative regulator of IL-6-type cytokine signaling. SOCS3 is i...

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Detalhes bibliográficos
Main Authors: Yan, Chunguang, Ward, Peter A., Wang, Ximo, Gao, Hongwei
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714578/
https://ncbi.nlm.nih.gov/pubmed/23585399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-225797
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