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Differential targeting of the dopamine transporter to recycling or degradative pathways during amphetamine- or PKC-regulated endocytosis in dopamine neurons

The dopamine transporter (DAT) clears the extracellular dopamine released during neurotransmission and is a major target for both therapeutic and addictive psychostimulant amphetamines. Amphetamine exposure or activation of protein kinase C (PKC) by the phorbol ester PMA has been shown to down-regul...

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Autores principales: Hong, Weimin C., Amara, Susan G.
Formato: Artigo
Lenguaje:Inglês
Publicado: Federation of American Societies for Experimental Biology 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714572/
https://ncbi.nlm.nih.gov/pubmed/23612789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-218727
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