Double-Blind, Randomized Study Evaluating the Glycemic and Anti-inflammatory Effects of Subcutaneous LY2189102, a Neutralizing IL-1β Antibody, in Patients With Type 2 Diabetes

OBJECTIVE: Inflammation is associated with pancreatic β-cell apoptosis and reduced insulin sensitivity. Literature suggests that interleukin (IL)-1β may contribute to the pathogenesis of type 2 diabetes mellitus (T2DM). This study aimed to determine the efficacy, safety, and tolerability of LY218910...

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Autores principales: Sloan-Lancaster, Joanne, Abu-Raddad, Eyas, Polzer, John, Miller, Jeffrey W., Scherer, Joel C., De Gaetano, Andrea, Berg, Jolene K., Landschulz, William H.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2013
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3714510/
https://ncbi.nlm.nih.gov/pubmed/23514733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/dc12-1835
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